Manchester City will be hoping to avoid suffering a fourth straight defeat for the first time under Pep Guardiola later.
The reigning champions make the trip to Brighton in today�s half-five kick-off.
Albion are also looking to get back to winning ways after two defeats to Liverpool last week.
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Liverpool sit top of the table heading into the weekend - and they welcome Aston Villa to Anfield in the late game.
Republic of Ireland goalkeeper Caoimhin Kelleher is set to start for the Reds, who are unbeaten in their last eight meetings with Villa.
In the 3pm kick-offs, there's a meeting of the bottom two with Wolves hosting Southampton, Everton go to West Ham, Crystal Palace take on Fulham in a London derby and Brentford play Bournemouth.
