Newcastle's sixth Premier League victory in a row has taken them up to second in the table.
They were 3-nil winners away at Leicester as the top flight returned for the first time since the World Cup.
A late goal for Wolves saw them beat Everton 2-1 at Goodison Park, meaning they leapfrog Southampton - who slip to the bottom - after their 3-1 home defeat to Brighton.
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Crystal Palace had two players sent off as they lost 3-nil to Fulham.
Harry Kane inspired a Tottenham fightback in the lunchtime kick-off as they came from behind to draw 2-all at Brentford.
Aston Villa kick-off against Liverpool later this hour, before Arsenal aim to extend their lead at the top when they host West Ham.
